oloa
Tetracaine hydrochloride
Fa'amatalaga o oloa
MF: C15H25ClN2O2
MW: 300.82
CAS: 136-47-0
1．Tetracaine hydrochloride ose fa'ama'i fa'apitonu'u sili ona aoga e mafai ona poloka ai le galuega a neura toe fa'afoliga.E faʻaaogaina i faʻamaʻi faʻamaʻi, faʻamaʻi poloka neura, faʻamaʻi faʻamaʻi, ma isi faʻatusatusa i le procaine, o lona aafiaga faʻapitonuʻu e taua tele, ma ua faʻaaogaina lautele i le falemaʻi.E ala i le suʻesuʻeina o auala faʻapipiʻi o loʻo i ai nei, o loʻo maua ai o le faʻaogaina o le p-butylamino benzoic acid o le laasaga autu lea i le faʻaogaina o le tetracaine hydrochloride, o loʻo i ai faʻaletonu o mea mataʻutia le tumau poʻo le maualalo o fua.Ua faaleleia e saienitisi lenei mea.I le 1981, na latou fuafua e faʻapipiʻi le p-butylamino benzoic acid e ala i le alkylating p-aminobenzoic acid ma le 1-Bromobutane.Ae ui i lea, ona o le le maalofia o le faʻavaeina o mea e maua mai i le dibutylation ma le natura le mautonu o mea mataʻutia, o lenei auala e le talafeagai mo le gaosiga o pisinisi.
2． Tetracaine hydrochloride e faʻaaogaina mo faʻamaʻi mucosal luga, faʻamaʻi faʻamaʻi, faʻamaʻi epidural ma faʻamaʻi subarachnoid;Fa'aoga mo fa'ama'i mata, e le fa'apipi'i toto toto, e le fa'aleagaina ai le epithelium o le mata, ma e le fa'atuputeleina ai le mamafa o le mata.
3．O lenei vailaʻau e mafai ona faʻaleleia ai le aʻafiaga o le neura o le cisatracurium, ma e tatau ona faʻaititia le fua o le mea mulimuli pe a tuʻufaʻatasia.Pe a tuʻufaʻatasia ma le adrenaline, e mafai ona faʻapipiʻi toto toto, faʻaitiitia le tafe toto, faʻagesegese le faʻaaogaina o fualaau faasaina, ma faʻaumiumi le umi o le gaioiga.Ae o le tuufaatasiga o ia mea e lua e le talafeagai mo tagata mamaʻi maʻi fatu, toto maualuga, hyperthyroidism, peripheral vascular maʻi ma isi.E mafai e le Hyaluronidase ona faʻateleina le faʻasalalauina o lenei vailaʻau, faʻavaveina le amataga o le faʻamaʻi, faʻaitiitia le fulafula i le lotoifale, ma puipuia le faʻavaeina o le hematoma.Ae ui i lea, e mafai foi e le hyaluronidase ona faʻavaveina le faʻaogaina o lenei vailaʻau, e mafua ai le faʻateleina o le vailaʻau faʻamaʻi oona o lenei vailaʻau.O lenei vailaʻau o se mea e maua mai i le p-aminobenzoic acid (PABA).Sulfonamides e fa'aolaina ai le fa'ama'i e ala i le taofia o le PABA o siama.Pe a tuʻufaʻatasia lenei vailaʻau ma sulfonamides, o le a faʻalavelaveina le aʻafiaga o le antibacterial, o lea e le tatau ai ona tuʻufaʻatasia le lua.O lenei vaila'au e fa'asa'o ma e le tatau ona fa'afefiloi ma vaila'au vai alkaline;E oʻo lava i vailaʻau faʻamaʻi e mafai ona aʻafia ai le tau faʻamaʻi o le vailaʻau ona o le pH eseese, e mafua ai le faʻaitiitia o gaioiga poʻo le tuai o le taimi amata.O sauniuniga o le iodine e mafai ona mafua ai le tafe o lenei vailaʻau, o lea e le mafai ai ona faʻaogaina le nofoaga o tui o lenei vailaʻau.
Fa'atatauga
O lenei oloa o se fa'ama'i fa'apitonu'u o le ester ua leva ona galue.O ona uiga gaioiga e: malosi le ulu atu i le mucosa, talafeagai mo faʻamaʻi luga, ma leai ni faʻalavelave faʻaleagaina e pei o le vasoconstriction, mydriasis, manua o le mata pe a uma le mata.E masani ona faʻaaogaina i le ophthalmology.Ole a'afiaga ole vai fa'apitonu'u ma le o'ona e tusa ma le 10 taimi sili atu nai lo le procaine.A maeʻa le tui, o le faʻamaʻi faʻamaʻi o le chemicalbook e faʻaalia lemu (pe a ma le 10 minute), ma e faʻagesegese foi le metabolism pe a uma le faʻaogaina.O le taimi fa'ama'i fa'apitonu'u e o'o i le 3ij, h, -j.e uiga i.E masani ona faʻaaogaina mo faʻamaʻi luga o mata, isu ma faʻaʻi mucosa, ma e seasea faʻaaogaina mo faʻamaʻi faʻamaʻi ma faʻamaʻi epidural.E masani lava, e le fa'aaogaina mo fa'ama'i infiltration ona o lona maualuga oona.
